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13.00 - Get together and Introduction
Session I (13:30 - 15:15) - Update on current ENS@T projects from the ACC and NAPACA Working group (chaired by B. Allolio)
13:30 - TIS11 family proteins and the control of mRNA stability in the adrenal cortex
N. Cherradi, Grenoble
13:45 - BMP dependent effects on adrenal tumorigenesis
I. Johnsen, Freiburg/Munich
14:00 - Potential role of type I interferons in adrenocortical carcinoma growth
L. Hofland, Rotterdam
14:15 - Phenotypical characterization of the NCI side population
F. Beuschlein / U. Lichtenauer, Munich/Freiburg
14:30 - Uppsala experience of the role of PET-scanning in management of ACC
B. Skogseid, Uppsala
14:45 - Prognostic markers of adrenal cortical tumors: a molecular approach and The Carney complex cohort: follow-up
J. Bertherat, Paris (from Session IV, Proposals)
15:00 Urinary steroid profiling via GC/MS in ACC - first results of EURINE ACC
W. Arlt, Birmingham
Coffee break (15:15-15:30)
Session II (15:30-17:15): Update on current ENS@T projects from the APA Working group (chaired by F. Mantero)
15:30 - Prospective comparison of the captopril and the saline infusion test for excluding primary aldosteronism due to aldosterone-producing adenoma: results of the PAPY Study and proposal for collaborative studies
G.P. Rossi and F. Mantero, Padua
15:45 - Prediction of outcome in 168 patients with PA having undergone adrenalectomy
E. Letavernier, Paris
16:00 - Introduction of the German Conn Registry
M. Quinkler, Berlin
16:15 - Role of endothelial cells in modulation of aldosterone release
I. Ansurudeen, Dresden
16:30 - Quantitative expression of urotensin-II and urotensin-II receptor in the normal human adrenal gland, aldosterone-producing adenomas and pheochromocytoma.
L. Giuliani, Padua
16:40 - G-protein coupled receptor expression in APA - microarray and RT-PCR results from Padua and Paris
B. Mariniello Padua and C. Zennaro, Paris
17:00 Aberrant receptor expression in PA - clinical characterization
O. Zwermann, Munich
Coffee break (17:15-17:30)
Session III (17:30-19:15): Update on current ENS@T projects from the Pheo Working group (chaired by P.-F. Plouin)
17:30 - Hereditary PGL in France: the PGL.NET cohort
A. P. Gimenez-Roqueplo, Paris
17:45 - Novel VHL mutations with unusual clinical presentation
T. Ercolino, Florence
18:00 - Novel markers and targets for the prognosis and treatment of malignant pheochromocytomas
Y. Anouar, Rouen
18:15 - SDHB gene mutations predict survival in patients with malignant PH and PGL
L. Amar, Paris
18:30 - Very low penetrance of SDHB mutation in three Italian families with a large number of carriers
G. Opocher, Padua
18:45 - Detection of large rearrangements in the PH/PGL genes using QMPSF
N. Burnichon, Paris
19:00 - A VHL intronic sequence variant associated with pheochromocytoma
F. Schiavi, Padua
Dinner (20:00 -23:00)
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Saturday, November 04:
Morning Session: Update on current "ENS@T projects" (09h00 - 12h00)
Session IV (09:00-11:00): Proposal for future ENS@T projects (chaired by M. Reincke)
09:00 - Special topic: How to set up a genetic screen for patients with sporadic PA
T. Meitinger, Munich
09:25 - Evaluation of adrenal masses: the 18-FDG approach
X. Bertagna, Paris (from Session I, ACC and NAPACA)
09:40 - The metabolic syndrome in patients with incidentally detected adrenal adenomas: evaluation of the outcome of adrenalectomy compared to conservative management
M. Terzolo, Torino
09:55 - Quality control in laboratory assessment of aldosterone and renin in biological fluids
M. Bidlingmaier, Munich
10:10 - Genetic regulation of aldosterone: interactions between CYP11B1 and CYP11B2
J. Connell, Glasgow
10:25 - Further implementation of a European database of Pheo/PGL gene mutations and polymorphisms
A. P. Gimenez-Roqueplo, Paris
10:40 - Multi-targeted tyrosin-kinase inhibitor - new options for refractory ACC patients - discussion of two potential phase II trials
A. Berruti, Torino and M. Fassnacht, Würzburg
Coffee break (11:00) and End of Session
ENS@T Steering committee meeting (11:00 - 14:00)
14:00 - End of Meeting
